m-Chloroperbenzoic acid → HCID 86689976、化合物
反応式
[C:1]([O:4][CH:5]([CH2:17][CH2:18][S:19][CH3:20])[C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[O:7])(=[O:3])[CH3:2].C1C=C(Cl)C=C(C(OO)=[O:29])C=1>ClCCl>[C:1]([O:4][CH:5]([CH2:17][CH2:18][S:19]([CH3:20])=[O:29])[C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[O:7])(=[O:3])[CH3:2]参加物
4
実験手順
To a solution of 4-(methylthio)-1-(octylamino)-1-oxobutan-2-yl acetate (6.33 g, 20.86 mmol) in dichloromethane (200 mL) at 0° C. was added mCPBA (77%, 4.67 g, 20.86 mmol). The resulting mixture was allowed to warm to room temperature with stirring overnight. The reaction was washed with saturated sodium bicarbonate (3×100 mL), 1N HCl (1×100 mL), and brine (1×100 mL). The organic layer was dried over magnesium sulfate, filtered and evaporated to give a yellow oil (6.7 g, 100%). m/z 320 (MH+).