HCID 15341804、化合物 → HCID 15341825、化合物
反応式
[OH:1][C:2]1[C:14]([CH2:15][CH:16]=[CH2:17])=[C:13]([OH:18])[CH:12]=[CH:11][C:3]=1[C:4]([N:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5]>C(O)C.[Pd]>[OH:1][C:2]1[C:14]([CH2:15][CH2:16][CH3:17])=[C:13]([OH:18])[CH:12]=[CH:11][C:3]=1[C:4]([N:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5]参加物
4
実験手順
1-[2,4-dihydroxy-3-(2-propenyl)benzoyl]pyrrolidine (750 mg) in 2 ml ethanol was hydrogenated at room temperature and 5 psi for three hours using 4% Pd/C as catalyst. The solvent was removed under vacuum and the residue was chromatographed on silica gel using 50/50 ethyl acetate/hexane as eluant to give the product (650 mg).
後処理
- customwas hydrogenated at room temperature
- customThe solvent was removed under vacuum
- customthe residue was chromatographed on silica gel using 50/50 ethyl acetate/hexane as eluant
出典と根拠
- ORDレコード
- ord-9a43f0cc9ea54ca981aade07061a6bc2
- 出典データセット
- uspto-grants-1995_08
- 特許番号
- US05439937
反応ノート
読み込み中…