Water → HCID 178443206、化合物

HRID 1756990ノート

反応式

HRID 1756990 の反応式
Cl.[NH2:2][OH:3].C(N(CC)CC)C.[C:11](#[N:24])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].O>C(O)C.O.C(O)C>[OH:3][NH:2][C:11](=[NH:24])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

参加物

7

反応物 4

HCID 962WaterHCID 8471TriethylamineHCID 12390TridecanenitrileHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 178443206HCID 178443206、化合物収率 26.5%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 19096565Water ethanol溶媒

実験手順

Hydroxylamine hydrochloride (0.90 g, 12.9 mmol) was added to a solution of triethylamine (1.79 mL, 12.9 mmol) in 50% ethanol/water (4 mL) and the mixture was stirred for 2 minutes. Tridecane nitrile (2.02 g, 10.4 mmol) in ethanol (10 mL) was added and the mixture refluxed for 2 hours, allowed to cool, and poured into water (50 mL). The precipitate was collected, stirred with hexanes, and filtered to yield a white solid (0.63 g, 26%).

後処理

  1. temperaturethe mixture refluxed for 2 hours
  2. temperatureto cool
  3. customThe precipitate was collected
  4. stirringstirred with hexanes
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-571455ffa192480696a3ed86f3b5ed48
出典データセット
uspto-grants-1995_08
特許番号
US05441975

反応ノート

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