Pyridine → HCID 19389470、化合物

HRID 1757047ノート

反応式

HRID 1757047 の反応式
[Si:1]([O:8][CH2:9][CH:10]1[O:15][C:14](=[O:16])[CH:13]=[C:12]([OH:17])[CH2:11]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].N1C=CC=CC=1.[C:24](Cl)(=[O:26])[CH3:25]>ClCCl>[C:24]([O:17][C:12]1[CH2:11][CH:10]([CH2:9][O:8][Si:1]([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2])[O:15][C:14](=[O:16])[CH:13]=1)(=[O:26])[CH3:25]

参加物

5

反応物 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 67809616HCID 67809616、化合物

生成物 1

HCID 19389470HCID 19389470、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To 6-t-butyldimethylsilyloxymethyl-5,6-dihydro-4-hydroxy-pyran-2-one (0.26 parts) in dichloromethane (3 cm3) at ambient temperature was added pyridine (0.1 parts) and then acetyl chloride (0.1 parts). After approximately 30 minutes at ambient temperature the reaction mixture was washed with water, dried over MgSO4 and evaporated to yield 4-acetoxy-6-t-butyldimethylsilyloxymethyl-5,6-dihydropyran-2-one (0.2 parts).

後処理

  1. washAfter approximately 30 minutes at ambient temperature the reaction mixture was washed with water
  2. dry with materialdried over MgSO4
  3. customevaporated

出典と根拠

ORDレコード
ord-cc4c16edcc854448b5c8b86d690ffaff
出典データセット
uspto-grants-1995_08
特許番号
US05443970

反応ノート

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