Water → HCID 19389481、化合物
反応式
[Si:1]([O:8][CH2:9][CH:10]1[O:15][C:14](=[O:16])[CH2:13][CH:12](O)[CH2:11]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1(C)C=CC=CC=1>[Si:1]([O:8][CH2:9][CH:10]1[O:15][C:14](=[O:16])[CH:13]=[CH:12][CH2:11]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]参加物
5
実験手順
6-t-Butyldimethylsilyloxymethyl-4-hydroxytetrahydropyran-2-one (1.0 parts) was dissolved in toluene and p-toluenesulphonic acid (0.1 parts) was added. The reaction mixture was heated at reflux with removal of water via a Dean and Stark apparatus. The cooled reaction mixture was then washed with water and evaporated to give 6-t-butyl dimethylsilyloxymethyl-5,6-dihydropyran-2-one (0.3 parts).
後処理
- temperatureThe reaction mixture was heated
- customThe cooled reaction mixture
- washwas then washed with water
- customevaporated
出典と根拠
- ORDレコード
- ord-85bda2480f794ae9bdb4ccfc88a25294
- 出典データセット
- uspto-grants-1995_08
- 特許番号
- US05443970
反応ノート
読み込み中…