Pyridine → HCID 19389482、化合物
反応式
[OH:1][CH:2]1[CH2:7][CH:6]([CH3:8])[O:5][C:4](=[O:9])[CH2:3]1.N1C=CC=CC=1.[S:16](Cl)([CH3:19])(=[O:18])=[O:17]>ClCCl>[S:16]([O:1][CH:2]1[CH2:7][CH:6]([CH3:8])[O:5][C:4](=[O:9])[CH2:3]1)([CH3:19])(=[O:18])=[O:17]参加物
5
実験手順
To a solution of 4-hydroxy-6-methyltetrahydropyran-2-one (1.5 parts) in dichloromethane (40 parts) was added pyridine (1.1 parts) and then, over 15 minutes, mesyl chloride (1.65 parts). The reaction was set aside at ambient temperature under N2 for 18 hours at which point GLC analysis indicated less than 1.5% of the starting material remained. The reaction mixture was filtered and the organic phase then washed with water before evaporating to obtain 4-mesyloxy-6-methyl-tetrahydropyran-2-one (0.5 parts).
後処理
- waitThe reaction was set aside at ambient temperature under N2 for 18 hours at which point GLC analysis
- filtrationThe reaction mixture was filtered
- washthe organic phase then washed with water
- custombefore evaporating
出典と根拠
- ORDレコード
- ord-f4dc6e204cbf4ae0a1de9bb56f0c35c9
- 出典データセット
- uspto-grants-1995_08
- 特許番号
- US05443970
反応ノート
読み込み中…