5-(3,4-Dimethoxy-5-chlorophenyl)-2,4-pentadienoic acid → 5-(3,4-Dimethoxy-5-chlorophenyl)pentanoic acid

HRID 1757638ノート

反応式

HRID 1757638 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:12]=[CH:13][CH:14]=[CH:15][C:16]([OH:18])=[O:17])[CH:6]=[C:7]([Cl:11])[C:8]=1[O:9][CH3:10]>C(O)(=O)C.Cl.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[CH:6]=[C:7]([Cl:11])[C:8]=1[O:9][CH3:10]

参加物

5

反応物 1

HCID 542197795-(3,4-Dimethoxy-5-chlorophenyl)-2,4-pentadienoic acid

生成物 1

HCID 193892435-(3,4-Dimethoxy-5-chlorophenyl)pentanoic acid

試薬・触媒・溶媒 3

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒HCID 313Hydrochloric Acid溶媒

実験手順

A solution containing 6.2 g of the above product obtained in Example 32 wasdissolved in a mixture of 30 ml of acetic acid and 3 ml of conc. hydrochloric acid. Palladium on charcoal catalyst (10% Pd) was added and the mixture was hydrogenated at normal pressure and room temperature. After filteration the solvents were evaporated in vacuo. Yield 3.2 g (55%), a viscous oil.

後処理

  1. customwas hydrogenated at normal pressure and room temperature
  2. customAfter filteration the solvents were evaporated in vacuo

出典と根拠

ORDレコード
ord-9269798c12624c638d081232970b0edc
出典データセット
uspto-grants-1995_08
特許番号
US05446194

反応ノート

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