4-Toluenesulfonyl chloride → 2,3-Dihydro-4-[(4-methylphenyl)sulfonyloximino]-2-phenyl-4H-1-benzopyran

HRID 1757952

反応式

HRID 1757952 の反応式
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[OH:12][N:13]=[C:14]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[O:17][CH:16]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:15]1>N1C=CC=CC=1>[CH3:11][C:1]1[CH:6]=[CH:5][C:4]([S:7]([O:12][N:13]=[C:14]2[C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=3[O:17][CH:16]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:15]2)(=[O:9])=[O:8])=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 73974-Toluenesulfonyl chlorideHCID 2483142,3-Dihydro-4-(hydroxyimino)-2-phenyl-4H-1-benzopyran

生成物 1

HCID 2483152,3-Dihydro-4-[(4-methylphenyl)sulfonyloximino]-2-phenyl-4H-1-benzopyran

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒2 回

実験手順

A solution of p-toluenesulfonyl chloride (83 g) in 125 ml pyridine was added dropwise at 5°-10° to 2,3-dihydro-4-(hydroxyimino)-2-phenyl-4H-1-benzopyran (52 g) in 230 ml pyridine. The reaction mixture was then stirred for 20 hours at room temperature, poured into ice-water to separate out the title compound, which was filtered, washed several times with water, then once with ether, and finally dried in air. Yield: 85.5 g; m.p. 141°-143°.

後処理

  1. customto separate out the title compound, which
  2. filtrationwas filtered
  3. washwashed several times with water
  4. dry with materialonce with ether, and finally dried in air

出典と根拠

ORDレコード
ord-67ef42dec5da44098a97b2815a83acfe
出典データセット
uspto-grants-1983_02
特許番号
US04371541

関連ノート

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