HCID 13102700、化合物 → 3-Pyridinamine, 6-(3,4-dichlorophenoxy)-

HRID 1758002ノート

反応式

HRID 1758002 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[Cl:18])[O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][N:7]=1>C(O)C.[Pd]>[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[Cl:18])[O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][N:7]=1

参加物

4

反応物 1

HCID 13102700HCID 13102700、化合物

生成物 1

HCID 5148873-Pyridinamine, 6-(3,4-dichlorophenoxy)-

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

The 2-(3,4-dichlorophenoxy)-5-nitropyridine described above was divided into 4 portions of 23.7 g each, and each portion was then hydrogenated in absolute ethanol employing a palladium catalyst as well known in the art. After removal of the catalyst, the ethanol filtrates were combined and evaporated to dryness. The residue which remained was diluted with isopropyl alcohol and hexane and then chilled. The resulting solid was collected by filtration and vacuum dried to give 70.8 g of 2-(3,4-dichlorophenoxy)-5-pyridinamine as a rose colored powder, m.p. 78°-79.3° C.

後処理

  1. customAfter removal of the catalyst
  2. customevaporated to dryness
  3. additionThe residue which remained was diluted with isopropyl alcohol and hexane
  4. temperaturechilled
  5. filtrationThe resulting solid was collected by filtration and vacuum
  6. customdried

出典と根拠

ORDレコード
ord-c413b7171c6c49f4bc18813bf7d962e8
出典データセット
uspto-grants-1983_02
特許番号
US04371537

反応ノート

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