Bromine → 1,4-Bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one

HRID 1758100ノート

反応式

HRID 1758100 の反応式
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([O:6][CH2:7][C:8](=[O:21])[C:9]([CH3:20])([CH3:19])[CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.[Br:24]Br>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([O:6][CH:7]([Br:24])[C:8](=[O:21])[C:9]([CH3:19])([CH3:20])[CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24408BromineHCID 127659691,4-Bis-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one

生成物 1

HCID 127659701,4-Bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one収率 100%

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

36.6 g (0.1 mole) of 1,4-bis-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one were dissolved in 250 ml of chloroform, and 16.6 g (0.1 mole) of bromine were added dropwise at 20° C. in a manner such that continuous decolorization occurred. After the addition, the mixture was subsequently stirred at room temperature for 30 minutes and was then concentrated by distilling off the solvent in vacuo. 43.2 g (quantitative conversion) of 1,4-bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one were obtained as an oil, which was further reacted directly. ##STR43##

後処理

  1. additionAfter the addition
  2. concentrationwas then concentrated
  3. distillationby distilling off the solvent in vacuo

出典と根拠

ORDレコード
ord-68c9349f95df476db7aca3d23abcede0
出典データセット
uspto-grants-1983_02
特許番号
US04371708

反応ノート

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