Hydrochloric Acid → HCID 54392493、化合物

HRID 1758112ノート

反応式

HRID 1758112 の反応式
[CH2:1]([C:4]1[CH:5]=[C:6]([C:11]([C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[C:16]([CH2:21][CH:22]=[CH2:23])[CH:15]=2)([CH3:13])[CH3:12])[CH:7]=[CH:8][C:9]=1[OH:10])[CH:2]=[CH2:3].[OH-].[K+].Cl>CO>[CH:21]([C:16]1[CH:15]=[C:14]([C:11]([C:6]2[CH:7]=[CH:8][C:9]([OH:10])=[C:4]([CH:1]=[CH:2][CH3:3])[CH:5]=2)([CH3:12])[CH3:13])[CH:19]=[CH:18][C:17]=1[OH:20])=[CH:22][CH3:23]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 74457Phenol, 4,4'-(1-methylethylidene)bis(2-(2-propen-1-yl)-

生成物 1

HCID 54392493HCID 54392493、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

反応条件

温度
110 °C

実験手順

400 ml of methanol is slowly added with stirring to a mixture of 3 mols of 2,2-bis-(3-allyl-4-hydroxyphenyl)-propane (A1) and potassium hydroxide pellets. The mixture is afterwards carefully heated to 110° C. with the distilling off of 116 ml of methanol. The reaction solution is subsequently held, with reflux cooling, for a further 6 hours at 110° C. The reaction solution is then cooled, neutralised with conc. HCl, and extracted with methylene chloride. The extract is dried, and completely evaporated to dryness to thus yield essentially pure 2,2-bis-[3-(1-propenyl)-4-hydroxyphenyl]-propane (A2), which at room temperature is a very highly viscous yellow liquid. The structural formula A2 is confirmed by microanalysis and H-NMR, MS and UV spectroscopy, as well as by means of gel-permeation chromatography.

後処理

  1. temperaturewith reflux
  2. temperatureThe reaction solution is then cooled
  3. extractionextracted with methylene chloride
  4. customThe extract is dried
  5. customcompletely evaporated to dryness

出典と根拠

ORDレコード
ord-288bc36db6cb417db4ada95839d5a92a
出典データセット
uspto-grants-1983_02
特許番号
US04371719

反応ノート

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