HCID 20509898、化合物 → HCID 20509920、化合物

HRID 1758234ノート

反応式

HRID 1758234 の反応式
[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[N+:14]([O-])=O>C(O)C.[Pd]>[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[NH2:14]

参加物

4

反応物 1

HCID 20509898HCID 20509898、化合物

生成物 1

HCID 20509920HCID 20509920、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

The crude aminoacetal obtained in step (c) is dissolved in 700 ml of ethanol and is hydrogenated at room temperature and at atmospheric pressure, in the presence of 3 g of palladium catalyst (10% Pd on carbon). After the catalyst is filtered off and the filtrate evaporated, the heading compound remains as an orange oil, which is converted into the hydrochloride using methanolic hydrochloric acid.

後処理

  1. filtrationAfter the catalyst is filtered off
  2. customthe filtrate evaporated

出典と根拠

ORDレコード
ord-8186f80460ea49798f8a047ceef94a27
出典データセット
uspto-grants-1983_02
特許番号
US04372956

反応ノート

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