Ethylenediamine → alpha-Thujene

HRID 1758592

反応式

HRID 1758592 の反応式
[Li].C(N)CN.[CH3:6][CH:7]([C:9]12[CH2:15][CH:14]1[C:12](=[CH2:13])[CH2:11][CH2:10]2)[CH3:8].CC([C@@]12C[C@@H]1C(=C)CC2)C>>[CH3:13][C:12]1[CH:14]2[CH2:15][C:9]2([CH:7]([CH3:8])[CH3:6])[CH2:10][CH:11]=1

参加物

5

反応物 4

HCID 3301EthylenediamineHCID 18818SabineneHCID 3028194LithiumHCID 10887971(+)-Sabinene

生成物 1

HCID 17868alpha-Thujene収率 69.3%

実験手順

0.48 g (69 millimoles) of lithium and 9 g (150 millimoles) of ethylenediamine were reacted in the atmosphere of air at a temperature of 128°-133° C. for 4 hours, and then mixed with 82 g of the above-prepared sabinene oil containing 35.7 g (262 millimoles) of (+)-sabinene. The mixture was allowed to react for 6 hours at 130° C. The reaction mixture was treated as described in Example 1 and thereafter, subjected to distillation at 60°-75° C. and 30 mmHg, affording 56.8 g of α-thujene oil containing 47.8% of (-)-α-thujene. The yield of (-)-α-thujene was 76.0%.

後処理

  1. customto react for 6 hours at 130° C
  2. additionThe reaction mixture was treated
  3. distillationsubjected to distillation at 60°-75° C.

出典と根拠

ORDレコード
ord-e7073b02230649dd8732239c2c2cacba
出典データセット
uspto-grants-1983_02
特許番号
US04374292

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