HCID 12803422、化合物 → 1-(2-Methoxyethyl)-4-phenylimidazolidin-2-one
反応式
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16]>[Pd].C(O)C>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:9][CH:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16]参加物
4
実験手順
The 1-(2-methoxyethyl)-4-phenyl-4-imidazolin-2-one (6.5 g) so obtained is next admixed with 10% palladium on carbon (0.7 g) in ethanol (50 ml). The mixture is thereafter hydrogenated at 50 psi at room temperature for four hours and the catalyst is filtered. Resultant filtrate is finally concentrated to yield racemic 1-(2-methoxyethyl)-4-phenyl-2-imidazolidone (6.0 g), [α]D20 =-0.2(c=1 in CHCl3).
後処理
- filtrationthe catalyst is filtered
- concentrationResultant filtrate is finally concentrated
出典と根拠
- ORDレコード
- ord-7cec78dbd0884ea285c883ff0da02de3
- 出典データセット
- uspto-grants-1982_07
- 特許番号
- US04339603
反応ノート
読み込み中…