Dimethylformamide → Hydroxytetradecane Ether

HRID 1760052

反応式

HRID 1760052 の反応式
[OH-].[Na+].[O:3]1[CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:4]1.[CH3:18]N(C)C=O>C1(C)C=CC=CC=1>[OH:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[CH3:6][CH2:5][O:3][CH2:4][CH3:18]

参加物

5

反応物 3

HCID 6228Dimethylformamide3 回HCID 14798Sodium HydroxideHCID 186041,2-Epoxytetradecane

生成物 1

HCID 87205352Hydroxytetradecane Ether

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
150 °C

実験手順

15.0 g (0.035 mol) of the polyerythritol prepared in Example 1 and 0.15 g of sodium hydroxide were dissolved in 20 ml of N,N-dimethylformamide while heating at 150° C. in a dried nitrogen gas flow, and stirred for 30 minutes. 14.8 g (0.070 mol) of 1,2-epoxytetradecane in 50 ml of N,N-dimethylformamide was added to the mixture, which was further stirred for four hours at 105° C. in a dried nitrogen gas flow. After the reaction, N,N-dimetylformamide was evaporated to obtain adcrude product. After dissolving the crude product in 100 ml of hot toluene and cooling the solution to room temperature, unreacted polyerythritol was filtered out. The toluene in the filtrate was evaporated in vaccuo to obtain 28.5 g of a white powdery desired product.

後処理

  1. stirringwas further stirred for four hours at 105° C. in a dried nitrogen gas flow
  2. customwas evaporated
  3. customto obtain adcrude product
  4. temperaturecooling the solution to room temperature
  5. filtrationunreacted polyerythritol was filtered out
  6. customThe toluene in the filtrate was evaporated in vaccuo

出典と根拠

ORDレコード
ord-448d1fad38044f098b84c61bdd5a2c44
出典データセット
uspto-grants-2005_01
特許番号
US06838544B2

関連ノート

読み込み中…