Dichloromethane → HCID 14280602、化合物
反応式
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][O:19][N:20]3[C:29](=O)[CH2:28][C:23]4([CH2:27][CH2:26][CH2:25][CH2:24]4)[CH2:22][CH:21]3[OH:31])[CH2:12][CH2:11]2)=[N:2]1.FC(F)(F)C(O)=O.C([SiH](CC)CC)C.C(Cl)[Cl:47]>>[ClH:47].[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][O:19][N:20]3[CH2:29][CH2:28][C:23]4([CH2:27][CH2:26][CH2:25][CH2:24]4)[CH2:22][C:21]3=[O:31])[CH2:12][CH2:11]2)=[N:2]1参加物
5
実験手順
To a solution prepared from 8-[3-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]propyloxy]-7-hydroxy-8-azaspiro[4.5]decan-9-one (4.7 g), 80 ml of CH2Cl2 and 40 ml of trifluoroacetic acid was added triethylsilane (1.8 ml) dropwise. The mixture was stirred at room temperature. After 1.5 hours, no starting material remained as judged by TLC.