HCID 14552383、化合物 → HCID 14552384、化合物
反応式
C1(C[NH:8][CH:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH:10]2[C:19]([O:21][CH2:22][CH3:23])=[O:20])C=CC=CC=1>[Pd].C(O)C>[NH2:8][CH:9]1[CH2:18][CH2:17][C:12]2([O:16][CH2:15][CH2:14][O:13]2)[CH2:11][CH:10]1[C:19]([O:21][CH2:22][CH3:23])=[O:20]参加物
4
実験手順
Ethyl 8-[(phenylmethyl)amino]-1,4-dioxaspiro[4.5]-decane-7-carboxylate (397.2 g, 1.3 mole) was combined with 2563 ml of ethanol and 80 g of 5% palladium on activated carbon and hydrogenated at 50 p.s.i. for 6 hours at 45°-50° C. The catalyst was separated by filtration, and the filtrate was evaporated. When taken up in methylene chloride a semi-solid precipitated and was filtered out. The filtratew was evaporated to yield 277.7 g (97.4%) of the title product.
後処理
- customThe catalyst was separated by filtration
- customthe filtrate was evaporated
- customprecipitated
- filtrationwas filtered out
- customThe filtratew was evaporated
出典と根拠
- ORDレコード
- ord-14ec0b95474a4bd4950a87148200a346
- 出典データセット
- uspto-grants-1989_05
- 特許番号
- US04826986
反応ノート
読み込み中…