Sodium Hydroxide → Benzofuran-7-Carboxylic Acid
反応式
[O:1]1[C:5]2[C:6]([C:10]([O:12]C)=[O:11])=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[CH:2]1.[OH-].[Na+]>CO>[O:1]1[C:5]2[C:6]([C:10]([OH:12])=[O:11])=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[CH:2]1参加物
4
実験手順
(1)-(i) A mixture of 420 mg of methyl benzofuran-7-carboxylate, 5 ml of an aqueous 10% sodium hydroxide solution and 5 ml of methanol is stirred at room temperature for 1 hour. The reaction mixture is evaporated to remove solvent. The residue is dissolved in water and the solution is acidified with 10% hydrochloric acid. The resultant crystals are collected by filtration and dried to give 321 mg of benzofuran-7-carboxylic acid as colorless crystals.
後処理
- customThe reaction mixture is evaporated
- customto remove solvent
- dissolutionThe residue is dissolved in water
- filtrationThe resultant crystals are collected by filtration
- customdried
出典と根拠
- ORDレコード
- ord-ee157fa10fc94d07a242545f44bb72fa
- 出典データセット
- uspto-grants-1989_05
- 特許番号
- US04829067
反応ノート
読み込み中…