Sodium Hydroxide → Sodium 4-[2-(4-isopropylbenzamido)ethoxy]benzoate

HRID 1762177

反応式

HRID 1762177 の反応式
[CH:1]([C:4]1[CH:24]=[CH:23][C:7]([C:8]([NH:10][CH2:11][CH2:12][O:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=2)=[O:9])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[OH-].[Na+:26]>CO.O>[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([C:8]([NH:10][CH2:11][CH2:12][O:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([O-:20])=[O:19])=[CH:16][CH:15]=2)=[O:9])=[CH:23][CH:24]=1)([CH3:3])[CH3:2].[Na+:26]

参加物

5

反応物 2

HCID 14798Sodium HydroxideHCID 30810274-(2-(4-Isopropylbenzamido)ethoxy)benzoic acid

生成物 1

HCID 23698334Sodium 4-[2-(4-isopropylbenzamido)ethoxy]benzoate収率 70.5%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

4-[2-(4-Isopropylbenzamido)ethoxy]benzoic acid (3.27 g) was dissolved in 50 ml of methanol, a solution of 0.40 g of sodium hydroxide in 5 ml of water was added thereto, the mixture was concentrated in vacuo, and crystallized residue was recrystallised from methanol to give 2.46 g of crystalline product, m.p. not lower than 300° C. IR γmaxKBr (cm-1): 1640, 1605.

後処理

  1. concentrationthe mixture was concentrated in vacuo
  2. customcrystallized residue
  3. customwas recrystallised from methanol

出典と根拠

ORDレコード
ord-7b32c7d60e314b2d994c5846a8455aac
出典データセット
uspto-grants-1989_05
特許番号
US04831055

関連ノート

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