Thionyl Chloride → HCID 14368348、化合物

HRID 1762200ノート

反応式

HRID 1762200 の反応式
[CH3:1][C:2]1[C:7]([CH2:8]O)=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>C(Cl)Cl>[CH3:1][C:2]1[C:7]([CH2:8][Cl:16])=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 143684562-Methyl-6-ureidobenzyl alcohol

生成物 1

HCID 14368348HCID 14368348、化合物収率 59.9%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A mixture of 6-methyl-2-ureidobenzyl alcohol (1 g) and thionyl chloride (0.66 g) in methylene chloride (20 ml) was stirred for 2 hours at room temperature and evaporated in vacuo. The residue was washed with water and dried in a desiccator to give 6-methyl-2-ureidobenzyl chloride (0.66 g).

後処理

  1. customevaporated in vacuo
  2. washThe residue was washed with water
  3. customdried in a desiccator

出典と根拠

ORDレコード
ord-b93b6c06c59747348eeaa8e72a8f001b
出典データセット
uspto-grants-1989_05
特許番号
US04831041

反応ノート

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