N,N,N',N'-Tetramethylethylenediamine → HCID 178506647、化合物

HRID 1762253ノート

反応式

HRID 1762253 の反応式
[C:1]1([S:7]([N:10]2[C:18]3[CH:17]=[CH:16][N:15]=[CH:14][C:13]=3[CH:12]=[CH:11]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CN(C)CCN(C)C.C([Li:31])(C)(C)C>O1CCCC1.CCCCC>[C:1]1([S:7]([N:10]2[C:18]3[CH:17]=[CH:16][N:15]=[CH:14][C:13]=3[CH:12]=[C:11]2[Li:31])(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

6

反応物 3

HCID 8037N,N,N',N'-TetramethylethylenediamineHCID 110106571-(Phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridineHCID 178418306HCID 178418306、化合物

生成物 1

HCID 178506647HCID 178506647、化合物

試薬・触媒・溶媒 2

HCID 8003Pentane溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 0.645 g (2.5 mmols) of 1-benzenesulphonyl-1H-pyrrolo[3,2-c]pyridine and 0.755 ml (5 mmols) of tetramethylethylenediamine in 5 ml of tetrahydrofuran was cooled to -70° C. and 5 mmols of tert-butyl lithium in pentane were added, care being taken that the temperature did not exceed -60° C. The reaction medium was then stirred to obtain a solution of 1-benzenesulphonyl-2-lithio-1H-pyrrolo[3,2-c]pyridine which was used as such.

後処理

  1. customdid not exceed -60° C

出典と根拠

ORDレコード
ord-4f6213eeae064dbf8619e63329f3de33
出典データセット
uspto-grants-1989_05
特許番号
US04831144

反応ノート

読み込み中…