3-Phenoxybenzyl alcohol → 2,2-Dimethyl-3-(3-cyclobutoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

HRID 1762617ノート

反応式

HRID 1762617 の反応式
[CH3:1][C:2]1([CH3:17])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH:10]2[CH2:13][CH2:12][CH2:11]2)=[O:8])[CH:3]1[C:14]([OH:16])=[O:15].O(C1C=C(C=CC=1)CO)C1C=CC=CC=1>C(Cl)(Cl)Cl>[CH3:1][C:2]1([CH3:17])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH:10]2[CH2:11][CH2:12][CH2:13]2)=[O:8])[CH:3]1[C:14]([OH:16])=[O:15].[CH3:17][C:2]1([CH3:1])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH:10]([CH3:13])[CH3:11])=[O:8])[CH:3]1[C:14]([O-:16])=[O:15]

参加物

5

反応物 2

HCID 262953-Phenoxybenzyl alcoholHCID 539623272,2-Dimethyl-3-(3-cyclobutoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

生成物 2

HCID 539623272,2-Dimethyl-3-(3-cyclobutoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acidHCID 736552712,2-Dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

Using the procedure of Example 9, (1R, cis, ΔZ) 2,2-dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and m-phenoxy-benzyl alcohol were reacted to obtain m-phenoxy-benzyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate with a specific rotation of [α]D20 =+42° C.±2° (c=0.5% in chloroform).

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-40f421ac94104e438d8c514564c5ebdd
出典データセット
uspto-grants-1989_05
特許番号
US04833163

反応ノート

読み込み中…