Homoallyl bromide → 4-Bromobutyldimethylchlorosilane

HRID 1762721ノート

反応式

HRID 1762721 の反応式
[Br:1][CH2:2][CH2:3][CH:4]=[CH2:5].[CH3:6][SiH:7]([CH3:9])[Cl:8]>CC(O)C.C1(C)C=CC=CC=1.O.Cl.Cl.Cl[Pt](Cl)(Cl)Cl>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][Si:7]([CH3:9])([CH3:6])[Cl:8]

参加物

6

反応物 2

HCID 21241Homoallyl bromideHCID 66108Chlorodimethylsilane

生成物 1

HCID 143834624-Bromobutyldimethylchlorosilane収率 75.7%

試薬・触媒・溶媒 3

HCID 16211507Platinate(2-), hexachloro-, hydrogen, hydrate (1:2:1), (OC-6-11)-触媒HCID 1140Toluene溶媒HCID 3776Isopropanol溶媒

反応条件

温度
60 °C

実験手順

Hexachloroplatinic acid hexahydrate (0.02 g, 0.039 mmole) was dissolved in a minimum of 2-propanol. This solution was dissolved in 75 ml toluene under argon. 2-propanol and water were removed by azeotropically distilling 25 ml of the toluene. The resulting solution was stirred and 6.17 g (0.046 mole) of 4-bromo-1-butene was added at 40° C. 4.32 g (0.046 mole) of dimethylchlorosilane was slowly added and the solution was heated to 60° C. and allowed to react for four hours. The mixture was distilled to remove the toluene. Further vacuum distillation yielded 8.0 g of product with a b.p. of 92°-95° C. at 5 mm Hg pressure. 'H NMR confirmed the structure.

後処理

  1. custom2-propanol and water were removed
  2. distillationby azeotropically distilling 25 ml of the toluene
  3. customto react for four hours
  4. distillationThe mixture was distilled
  5. customto remove the toluene
  6. distillationFurther vacuum distillation

出典と根拠

ORDレコード
ord-a15d1ae6b3414632a1b2c5cd706dd8db
出典データセット
uspto-grants-1989_05
特許番号
US04833262

反応ノート

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