Acetic Anhydride → HCID 20309436、化合物
反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:9]=[CH:10][C:11](=[O:14])[NH:12][N:13]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>N1C=CC=CC=1>[C:15]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:9]=[CH:10][C:11](=[O:14])[NH:12][N:13]=1)(=[O:17])[CH3:16]参加物
4
実験手順
A mixture of 6-(2-hydroxyphenyl)-3(2H)-pyridazinone (20 g), acetic anhydride (60 ml) and pyridine (10 drops) was heated and stirred on a steam-bath for 13/4 hours. The mixture was evaporated under reduced pressure, and the residual oil was treated with water (100 ml) and methanol (10 ml) and was allowed to crystallise to give 6-(2-acetoxyphenyl)-3(2H)-pyridazinone (22.7 g) m.p. 181°-183.5°. A sample recrystallised from 50% aqueous ethanol had m.p. 182.5°-184.5°.
後処理
- temperaturewas heated
- customThe mixture was evaporated under reduced pressure
- additionthe residual oil was treated with water (100 ml) and methanol (10 ml)
- customto crystallise
出典と根拠
- ORDレコード
- ord-f8c1a66e89a547c4b2ec2ab8a9dfa4bc
- 出典データセット
- uspto-grants-1978_09
- 特許番号
- US04111935
反応ノート
読み込み中…