Epibromohydrin → HCID 20309580、化合物

反応式

[OH:1][C:2]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5].[CH2:18]([CH:20]1[O:22][CH2:21]1)Br>>[O:22]1[CH2:21][CH:20]1[CH2:18][O:1][C:2]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5]

参加物

反応物 2

HCID 18430Epibromohydrin

HCID 143636Propionic acid, 3-(6-hydroxy-m-anisoyl)-, methyl ester

生成物 1

HCID 20309580HCID 20309580、化合物

実験手順

Methyl 3-(2-hydroxy-5-methoxybenzoyl)propionate was reacted with epibromohydrin in a similar manner to that described in Example 1 (ii) to give methyl 3-[2-(2,3-epoxypropoxy)-5-methoxybenzoyl]propionate which, recrystallised from ether-petroleum ether (b.p. 60°-80°), had m.p. 50° - 51.5° C). (Found: C, 60.91; H, 6.07; C15H18O6 requires: C, 61.21; H, 6.17%).

出典と根拠

ORDレコード: ord-4710d8d4b147449ab56e9c0261dbf134
出典データセット: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04111936

反応ノート

読み込み中…

参加物