Hydrazinecarboxaldehyde → 6-[3-Chloro-5-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine
反応式
ClC1C=C(C=C(C(F)(F)F)C=1)C=O.Cl[C:15]1[N:16]=[N:17][C:18]([C:21]2[CH:26]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:24]=[C:23]([Cl:31])[CH:22]=2)=[CH:19][CH:20]=1.[CH:32]([NH:34][NH2:35])=O>C(O)CCC>[Cl:31][C:23]1[CH:22]=[C:21]([C:18]2[CH:19]=[CH:20][C:15]3[N:16]([CH:32]=[N:34][N:35]=3)[N:17]=2)[CH:26]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:24]=1参加物
5
実験手順
As described in Example 35, 3-chloro-5-(trifluoromethyl)benzaldehyde is converted to 3-chloro-6-[3-chloro-5-(trifluoromethyl)phenyl]pyridazine. This compound is reacted with formylhydrazine in refluxing n-butanol for 24 hours to give the product of the example.
後処理
- customto give the product of the example
出典と根拠
- ORDレコード
- ord-1e25b41548ad4e19942674e318651ba5
- 出典データセット
- uspto-grants-1978_09
- 特許番号
- US04112095
反応ノート
読み込み中…