Hydrochloric Acid → O-Methyltyrosine

HRID 1763740

反応式

HRID 1763740 の反応式
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([CH2:7][CH:8]2[NH:12]C(=O)N[C:9]2=[O:14])=[CH:5][CH:4]=1.[OH-:17].[Na+].Cl>O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH:8]([C:9]([OH:14])=[O:17])[NH2:12])=[CH:15][CH:16]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 957275-(4-Methoxy-benzyl)-hydantoin

生成物 1

HCID 97118O-Methyltyrosine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 148 g. of 5-p-methoxybenzyl hydantoin and 188 g. of sodium hydroxide in one liter of water is heated at reflux for 25 hours. The solution is cooled and made acid to pH 1 with concentrated hydrochloric acid. The formed solid is separated by filtration, washed with water and dried to give the above named compound, mp. 255° C. dec.

後処理

  1. temperatureat reflux for 25 hours
  2. temperatureThe solution is cooled
  3. customThe formed solid is separated by filtration
  4. washwashed with water
  5. customdried
  6. customto give the

出典と根拠

ORDレコード
ord-ad2f9784c50e47a380a258bb024a23b0
出典データセット
uspto-grants-1978_09
特許番号
US04111923

関連ノート

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