Methanol → HCID 22768536、化合物

HRID 1764488ノート

反応式

HRID 1764488 の反応式
[O:1]=[C:2]1[CH:6]([CH3:7])[O:5][CH:4]([CH3:8])[CH:3]1[C:9]([O:11][CH2:12][CH3:13])=[O:10].CO>C(O)C1C=CC=CC=1>[O:1]=[C:2]1[CH:6]([CH3:7])[O:5][CH:4]([CH3:8])[CH:3]1[C:9]([O:11][CH2:12][C:13]1[CH:7]=[CH:6][CH:2]=[CH:3][CH:4]=1)=[O:10]

参加物

4

反応物 2

HCID 887MethanolHCID 22768534Ethyl 2,5-dimethyl-4-oxooxolane-3-carboxylate

生成物 1

HCID 22768536HCID 22768536、化合物収率 168.7%

試薬・触媒・溶媒 1

HCID 244Benzyl Alcohol溶媒

実験手順

40 g of 4-oxo-2,5-dimethyl-3-carboethoxytetrahydrofuran in 200 ml of benzyl alcohol are heated at 180°-200° C. The methanol formed is distilled off. The excess benzyl alcohol is distilled off under reduced pressure and the residue is fractionated. 45 g (corresponding to 78% of theory) of 4-oxo-2,5-dimethyl-3-carbobenzyloxytetrahydrofuran of boiling point 102° C/0.02 mm Hg and refractive index nD25 = 1.5070 are obtained.

後処理

  1. distillationis distilled off
  2. distillationThe excess benzyl alcohol is distilled off under reduced pressure

出典と根拠

ORDレコード
ord-fcaffd7d8da140538ac716f8d8dcf6fe
出典データセット
uspto-grants-1978_09
特許番号
US04116982

反応ノート

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