Acetic Acid → HCID 12875270、化合物
反応式
C=O.[ClH:3].[CH3:4][C:5]1[S:6][C:7]([Cl:11])=[CH:8][C:9]=1[Cl:10].[C:12](O)(=O)C>>[Cl:3][CH2:12][C:8]1[C:9]([Cl:10])=[C:5]([CH3:4])[S:6][C:7]=1[Cl:11]参加物
5
反応条件
- 温度
- 70 °C
実験手順
8.6 G. (0.107 mol) off formalin and 90 ml. of concentrated hydrochloric acid were added to a solution of 10.87 g. (0.065 mol) of 2-methyl-3,5-dichlorothiophene in 45 ml. of acetic acid. The resulting mixture was heated to 70° C. for 18 hrs., cooled, poured into ice water and extracted with ether. The organic solution was washed with water, sodium bicarbonate and water, dried and evaporated to yield 3-chloromethyl-2,4-dichloro-5-methylthiophene as a crude oil.
後処理
- temperature, cooled
- extractionextracted with ether
- washThe organic solution was washed with water, sodium bicarbonate and water
- customdried
- customevaporated
出典と根拠
- ORDレコード
- ord-47d63f94b621427baf8d509b3ff27918
- 出典データセット
- uspto-grants-1978_09
- 特許番号
- US04116975
反応ノート
読み込み中…