Hydrazinecarboxaldehyde → 6-(p-Bromophenyl)-1,2,4-triazolo[4,3-b]pyridazine

HRID 1764637

反応式

HRID 1764637 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[N:10][C:11](Cl)=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[CH:15]([NH:17][NH2:18])=O>C(O)CCC>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]3[N:10]([CH:15]=[N:17][N:18]=3)[N:9]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 12229HydrazinecarboxaldehydeHCID 64052553-(4-Bromophenyl)-6-chloropyridazine

生成物 1

HCID 227689336-(p-Bromophenyl)-1,2,4-triazolo[4,3-b]pyridazine

試薬・触媒・溶媒 1

HCID 2631-Butanol溶媒

実験手順

A mixture of 3.76 g. of 3-(p-bromophenyl)-6-chloropyridazine, 1.80 g. of formylhydrazine and 50 ml. of butyl alcohol is heated to reflux and allowed to reflux overnight. The reaction mixture is allowed to cool and the precipitated product is washed with water, air dried and recrystallized from methyl alcohol, m.p. 209°-211° C.

後処理

  1. additionA mixture of 3.76 g
  2. temperatureto reflux
  3. temperatureto reflux overnight
  4. temperatureto cool
  5. washthe precipitated product is washed with water, air
  6. customdried
  7. customrecrystallized from methyl alcohol, m.p. 209°-211° C.

出典と根拠

ORDレコード
ord-75431e61e93e4b2a95d18a4233c3c94c
出典データセット
uspto-grants-1978_09
特許番号
US04117130

関連ノート

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