m-Chloroperbenzoic acid → HCID 69508187、化合物
反応式
ClC1C=CC=C(C(OO)=[O:9])C=1.[F:12][C:13]([C:16]1[C:17]([O:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[C:18]([C:22]2[CH2:26][CH2:25][CH2:24][C:23]=2[C:27]2[CH:28]=[N:29][CH:30]=[C:31]([CH:35]=2)[C:32]([OH:34])=[O:33])[CH:19]=[CH:20][CH:21]=1)([F:15])[F:14]>O1CCOCC1>[F:12][C:13]([C:16]1[C:17]([O:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[C:18]([C:22]2[CH2:26][CH2:25][CH2:24][C:23]=2[C:27]2[CH:28]=[N+:29]([O-:9])[CH:30]=[C:31]([CH:35]=2)[C:32]([OH:34])=[O:33])[CH:19]=[CH:20][CH:21]=1)([F:15])[F:14]参加物
4
実験手順
3-Chloroperbenzoic acid (25 mg, 0.11 mmol) was added to a solution of 5-{2-[trifluoromethyl-2-(benzyloxy)phenyl]cyclopent-1-enyl}nicotinic acid (44 mg, 0.1 mmol) in dioxan (2 ml) and left overnight at room temperature. The resulting mixture was evaporated to dryness and purified by preparative mass directed chromatography to give the title compound as an off-white solid (8 mg, 18%).