Dimethylamine → N,N-Dimethylbenzenesulfonamide
反応式
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:11][NH:12][CH3:13].O>C1COCC1>[CH3:11][N:12]([CH3:13])[S:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:9])=[O:8]参加物
5
実験手順
A solution of benzenesulfonylchloride (10 ml; 78 mmol) in THF (100 ml) was added a 40% solution of dimethylamine in H2O (20 ml; 160 mmol) such that the reaction temperature was kept below 50° C. The reaction mixture was stirred 1 h at rt. The reaction mixture was added H2O and THF removed by evaporation. The precipitate formed was isolated by filtration and air dried to give 14 g (97%) of N,N-dimethylbenzenesulfonamide.
後処理
- customwas kept below 50° C
- customremoved by evaporation
- customThe precipitate formed
- customwas isolated by filtration and air
- customdried
出典と根拠
- ORDレコード
- ord-167d462daca34ec2a30e9a8fc776f5ac
- 出典データセット
- uspto-grants-2007_06
- 特許番号
- US07235548B2
反応ノート
読み込み中…