1,1'-Carbonyldiimidazole → 2-(5,6-dimethylpyridin-3-yl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][C:12]1[CH:13]=[N:14][C:15]([CH3:19])=[C:16]([CH3:18])[CH:17]=1)(=[O:10])=[O:9].[C:20](N1C=CN=C1)(N1C=CN=C1)=[O:21]>ClCCCl>[CH3:18][C:16]1[CH:17]=[C:12]([N:11]2[C:20](=[O:21])[NH:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[S:8]2(=[O:10])=[O:9])[CH:13]=[N:14][C:15]=1[CH3:19]参加物
4
実験手順
The title compound (2.17 g, 7.15 mmol) was prepared from 2-amino-N-(5,6-dimethylpyridin-3-yl)benzenesulfonamide (2.7 g, 13.0 mmol) and 1,1′-carbonyldiimidazole (4.74 g, 29.2 mmol) in 1,2-dichloroethane (25 mL) at 110° C. for 3 h using the methods of (IntA14), step 3.
出典と根拠
- ORDレコード
- ord-95ade9df5a2047db95f860e5777f1ee8
- 出典データセット
- uspto-grants-2016_02
- 特許番号
- US09249160B2
反応ノート
読み込み中…