1H-1,2,4-Triazole → 1-(3,4,4-trifluoro-1-oxo-3-butenyl)-1H-1,2,4-triazole

関与物質

反応手順

To a solution of 1,2,4-triazole (1.38 g, 20 mmol) in ethyl acetate (100 mL) was added 3,4,4-trifluoro-3-butenoyl chloride (1.59 g, 10 mmol) at r.t. with stirring. The mixture was stirred for 30 min end filtered. The residue obtained after evaporation of the solvent was redissolved in dichloromethane (25 mL) end filtered. Evaporation of the solvent gave 1.8 g (94%) of the desired product as a clear oil.

情報源と証拠