HCID 12674909、化合物 → 5-Ethyl-4-methyl-2-pyrrolidinone
反応式
[CH3:1][CH:2]([CH:8]([N+:11]([O-])=O)[CH2:9][CH3:10])[CH2:3][C:4](OC)=[O:5]>CCO.O=[Pt]=O>[CH2:9]([CH:8]1[NH:11][C:4](=[O:5])[CH2:3][CH:2]1[CH3:1])[CH3:10]参加物
4
実験手順
A solution of 4.0 g (21 mmol) of methyl 3-methyl-4-nitrohexanoate (from step A) in 20 mL of EtOH containing 0.4 g of PtO2 was hydrogenated on a Parr apparatus for 3 days. The catalyst was filtered and washed with EtOH and the filtrate was concentrated. Vacuum distillation of the residue furnished 1.6 g (61%) of the title compound: bp 102°-107° C./2 mm.
後処理
- filtrationThe catalyst was filtered
- washwashed with EtOH
- concentrationthe filtrate was concentrated
- distillationVacuum distillation of the residue
出典と根拠
- ORDレコード
- ord-7a267f5c1d0b4743ad1a1378bb0caa1a
- 出典データセット
- uspto-grants-1997_05
- 特許番号
- US05629322
反応ノート
読み込み中…