1-Bromodecane → 1-Decyl-3,5-dimethyl-1,2,4-triazole

HRID 1780792

反応式

HRID 1780792 の反応式
[CH3:1][C:2]1[N:6]=[C:5]([CH3:7])[NH:4][N:3]=1.Br[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[OH-].[Na+]>CN(C)C=O.O>[CH2:9]([N:3]1[C:2]([CH3:1])=[N:6][C:5]([CH3:7])=[N:4]1)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

参加物

6

反応物 3

HCID 81731-BromodecaneHCID 14798Sodium HydroxideHCID 1390011H-1,2,4-Triazole, 3,5-dimethyl-

生成物 1

HCID 190476431-Decyl-3,5-dimethyl-1,2,4-triazole

試薬・触媒・溶媒 2

HCID 962Water溶媒2 回HCID 6228Dimethylformamide溶媒

反応条件

温度
120 °C

実験手順

A mixture of 3,5-dimethyl-1,2,4-triazole (6.0 parts; 0.062 mol ex (b) above) and 1-bromodecane (14.4 parts; 0.065 mol) in dimethylformamide (16 ml) was heated together at 120° C. for 23 hours. The cooled reaction mixture was diluted with water (100 ml), a solution of sodium hydroxide (2.62 parts; 0.065 mol) in water (100 ml) added, and the product extracted into ether (3×50 ml). After drying over magnesium sulphate the solution was evaporated to yield a pale yellow oil (3.3 parts; 22% theory).

後処理

  1. customThe cooled reaction mixture
  2. extractionthe product extracted into ether (3×50 ml)
  3. dry with materialAfter drying over magnesium sulphate the solution
  4. customwas evaporated
  5. customto yield a pale yellow oil (3.3 parts; 22% theory)

出典と根拠

ORDレコード
ord-93dd2a57937143018e7246596ef88f0f
出典データセット
uspto-grants-1997_05
特許番号
US05631274

関連ノート

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