HCID 19707490、化合物 → Methyl 3-(3-aminophenoxy)benzoate
反応式
[C:1]([C:5]1[CH:6]=[C:7]([O:11][C:12]2[CH:13]=[C:14]([N+:18]([O-])=O)[CH:15]=[CH:16][CH:17]=2)[CH:8]=[CH:9][CH:10]=1)([O:3][CH3:4])=[O:2]>CO.[Pd]>[C:1]([C:5]1[CH:6]=[C:7]([O:11][C:12]2[CH:13]=[C:14]([NH2:18])[CH:15]=[CH:16][CH:17]=2)[CH:8]=[CH:9][CH:10]=1)([O:3][CH3:4])=[O:2]参加物
4
実験手順
To a solution of 41 (440 mg) in 30 mL of methanol under a nitrogen atmosphere was added 10% Pd/C (30 mg). The solution was purged with H2 gas, then stirred at room temperature under a balloon atmosphere of H2. After 8 h, the reaction was flushed with nitrogen and filtered through celite to remove the catalyst, then concentrated in vacuo. The resulting brown oil was used without further purification.
後処理
- customThe solution was purged with H2 gas
- customthe reaction was flushed with nitrogen
- filtrationfiltered through celite
- customto remove the catalyst
- concentrationconcentrated in vacuo
- customThe resulting brown oil was used without further purification
出典と根拠
- ORDレコード
- ord-d023a98feec84e08ba522c49b602c4f9
- 出典データセット
- uspto-grants-1997_05
- 特許番号
- US05631280
反応ノート
読み込み中…