2-Amino-5-chlorobenzenesulphonamide → 7-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide

HRID 17844

反応式

HRID 17844 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH:13]([O-])([O-])OCC>>[Cl:8][C:5]1[CH:6]=[CH:7][C:2]2[NH:1][CH:13]=[N:12][S:9](=[O:11])(=[O:10])[C:3]=2[CH:4]=1

参加物

3

反応物 2

HCID 122955502-Amino-5-chlorobenzenesulphonamideHCID 53630039Ethylorthoformate

生成物 1

HCID 100362767-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide

実験手順

A mixture of 2-amino-5-chlorobenzenesulphonamide (obtained according to J. Chem. Soc. Perkin I, 1043-1047, 1979) and ethyl orthoformate (40 mL) is heated at boiling for 30 minutes in an open vessel. The volume of the mixture is reduced by half under reduced pressure. The precipitate obtained is collected by filtration, washed with ether and dried.

後処理

  1. temperatureis heated
  2. customThe precipitate obtained
  3. filtrationis collected by filtration
  4. washwashed with ether
  5. customdried

出典と根拠

ORDレコード
ord-6b717345c1614eb9a2a1a77154c00af2
出典データセット
uspto-grants-2010_06
特許番号
US07741320B2

関連ノート

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