Methyl iodide → 2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium iodide
反応式
[CH3:1][N:2]([CH3:8])[CH2:3][CH:4]([OH:7])[CH2:5][OH:6].[CH3:9][I:10]>C(Cl)Cl>[I-:10].[OH:7][CH:4]([CH2:5][OH:6])[CH2:3][N+:2]([CH3:9])([CH3:8])[CH3:1]参加物
4
実験手順
To 1 mol of 3-(dimethylamino)-1,2-propanediol 20 (1.2 g) dissolved in CH2Cl2 (5 mL), MeI (2 g, 1.5 mol) was added and the mixture stirred at rt for 1 h. The solution was then filtered and the filtrated recristalise in MeOH/Ether and dried in vacuo. (yield 100%). The characterization data were consistent with the proposed structure.
後処理
- filtrationThe solution was then filtered
- dry with materialthe filtrated recristalise in MeOH/Ether and dried in vacuo
出典と根拠
- ORDレコード
- ord-1cedecc8418f46aa933e6e0e4a7420d3
- 出典データセット
- uspto-grants-2009_03
- 特許番号
- US07507859B2
反応ノート
読み込み中…