反応式
[F:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]=[C:12]([CH3:14])[NH:11][N:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1.[H-].[Na+].Cl[CH2:18][CH2:19][C:20]([NH:23][C:24](=[O:30])[O:25][C:26]([CH3:29])([CH3:28])[CH3:27])([CH3:22])[CH3:21]>CN1C(=O)N(C)CCC1.[I-].C([N+](CCCC)(CCCC)CCCC)CCC>[F:8][C:6]1[CH:5]=[C:4]([C:9]2[N:13]=[C:12]([CH3:14])[N:11]([CH2:18][CH2:19][C:20]([NH:23][C:24](=[O:30])[O:25][C:26]([CH3:29])([CH3:28])[CH3:27])([CH3:22])[CH3:21])[N:10]=2)[CH:3]=[C:2]([F:1])[CH:7]=1参加物
6
実験手順
3.74 g (19 mmol) of 3-(3,5-difluoro-phenyl)-5-methyl-[1,2,4]triazole in 25 mL DMPU are reacted with 0.92 g (23 mmol, 60%) of sodium hydride, 6.37 g (29 mmol) of tert.butyl (3-chloro-1,1-dimethyl-propyl)-carbamate and 1.27 g (3.5 mmol) of tetrabutylammonium iodide analogously to P-1-c). Oil.
出典と根拠
- ORDレコード
- ord-be8785509a74442a8b9d8d877d506d40
- 出典データセット
- uspto-grants-2009_03
- 特許番号
- US07511067B2
関連ノート
読み込み中…