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HRID 1788430作成日：2026年10月25日

3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid → 2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid

https://huagongshe.com/reaction/1788430

反応式

関与物質

役割名称HCID仕込み量
反応物3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acidHCID 5276167—
反応物(2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acidHCID 6957986—
生成物2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acidHCID 527619836%

反応手順

The general procedure described for Compound 242 was used with Fmoc-Tyr Wang resin (125 mg, 0.8 mmol/g), producing 22 mg of the title compound (36% yield). MS: 610.22 (M−H+) HPLC Procedure A, retention time=16.14 min.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07511145B2
出典データセットuspto-grants-2009_03
ORD IDord-cb5c027e03e6415d968c993d4dbb6529
出典メモuspto-grants-2009_03