3-Dimethoxymethyl-4-nitro-benzoic Acid Methyl Ester → 3-Dimethoxymethyl-4-nitro-benzoic Acid
反応式
C[O:2][C:3](=[O:18])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[C:6]([CH:13]([O:16][CH3:17])[O:14][CH3:15])[CH:5]=1>CO.[OH-].[Na+]>[CH3:17][O:16][CH:13]([O:14][CH3:15])[C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][C:7]=1[N+:10]([O-:12])=[O:11])[C:3]([OH:18])=[O:2]参加物
4
実験手順
To a solution of 5.49 g (21.5 mmol) of Compound 5 in 200 mL of methanol, 50 mL of 1M NaOH were added and the mixture was stirred at room temperature for 2 h. The reaction mixture was then evaporated to dryness, the residue was dissolved in 100 mL water, acidified with 1 M HCl to pH 3-4. The precipitate was then filtered off, washed with water (4×), and dried. Yield: 4.96 g (95%).
後処理
- customThe reaction mixture was then evaporated to dryness
- dissolutionthe residue was dissolved in 100 mL water
- filtrationThe precipitate was then filtered off
- washwashed with water (4×)
- customdried
出典と根拠
- ORDレコード
- ord-28d046793373421aa5344a8501d964e6
- 出典データセット
- uspto-grants-2009_03
- 特許番号
- US07511145B2
反応ノート
読み込み中…