化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → HCID 178480903、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | N-[4-(1-Hydroxy-2-(1H-imidazol-1-yl)ethyl]phenyl]methanesulfonamide | HCID 13763390 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178480903 | HCID 178480903 | — |
反応手順
Heat a solution of 4.0 g (14.2 mmole) of (±)-N-[4-[1-hydroxy-2-(1H-imidazol-1-yl)ethyl]phenyl]methanesulfonamide, 2 ml (32.1 mmole) of iodomethane and 50 ml methanol in a glass pressure tube to 80° C. for 24 hours. Remove the solvent in vacuo. Crystallize the residue from acetone. Recrystallize from acetone to provide the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04689341 |
| 出典データセット | uspto-grants-1987_08 |
| ORD ID | ord-057cda30ba974403950321e96ed564fa |
| 出典メモ | uspto-grants-1987_08 |