(3-Methoxybenzyl)triphenylphosphonium Chloride → HCID 69593617、化合物

HRID 1790394ノート

反応式

HRID 1790394 の反応式
[Cl-].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][CH:29]=1)[CH2:7][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:30]([N:32]([CH2:46][CH3:47])[C:33]([N:35]1[C:43]2[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=2)[C:37]([CH:44]=O)=[CH:36]1)=[O:34])[CH3:31]>O1CCCC1>[CH2:46]([N:32]([CH2:30][CH3:31])[C:33]([N:35]1[C:43]2[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=2)[C:37]([CH:44]=[CH:7][C:6]2[CH:27]=[CH:28][CH:29]=[C:4]([O:3][CH3:2])[CH:5]=2)=[CH:36]1)=[O:34])[CH3:47]

参加物

4

反応物 2

HCID 11407464(3-Methoxybenzyl)triphenylphosphonium ChlorideHCID 136006161-Diethylcarbamoyl-3-formylindole

生成物 1

HCID 69593617HCID 69593617、化合物収率 59.2%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

3-Methoxybenzyltriphenylphosphonium chloride (1.71 g) and 1-diethylcarbamoyl-3-formylindole (1.71 g), which had been synthesized according to the method of Tetrahedron Lett., 1869 (1986)., were reacted in tetrahydrofuran (5 ml) as in the above Production Example 41-1 to give the title compound (0.842 g) as a brown oil (yield: 59.1%). (59-2) 1-Diethylcarbamoyl-3-(3-methoxyphenethyl)indole

出典と根拠

ORDレコード
ord-64f40cb0f4e94dffa304fb3cc84114ca
出典データセット
uspto-grants-2006_07
特許番号
US07071201B2

反応ノート

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