Acetic Acid → 3-[4-(Thiazole-2-carbonyl)-piperazin-1-yl]-azetidine-1-carboxylic acid tert-butyl ester

反応式

[C:21](=[O:22])([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[N:28]1[CH2:29][C:30](=[O:32])[CH2:31]1.[CH3:38][C:39](=[O:40])[OH:41].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[N:8]1([C:14](=[O:15])[c:16]2[s:17][cH:18][cH:19][n:20]2)[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[Na+:37].[O-:33][C:34]([OH:35])=[O:36]>>[N:8]1([C:14](=[O:15])[c:16]2[s:17][cH:18][cH:19][n:20]2)[CH2:9][CH2:10][N:11]([CH:30]2[CH2:29][N:28]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:31]2)[CH2:12][CH2:13]1