Sodium Hydroxide → 2-(1H-imidazol-2-yl)benzonitrile
反応式
Cl.[NH:2]1[CH:6]=[CH:5][N:4]=[C:3]1[C:7]1[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=1[C:9]#[N:10].[OH-].[Na+]>O>[NH:2]1[CH:6]=[CH:5][N:4]=[C:3]1[C:7]1[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=1[C:9]#[N:10]参加物
4
実験手順
To a solution of 2-(1H-imidazol-2-yl)-benzonitrile hydrochloride (3 g, 0.014 mol) in water (20 ml) was added sodium hydroxide solution (2.5 N, 5 ml). Filtration of the resultant precipitate and recrystallization from ethyl acetate gave 2-(1H-imidazol-2-yl)-benzonitrile; Anal. Calcd. For C10H7N3: C, 70.99; H, 4.17; N, 24.84. Found: C, 70.74; H, 4.08; N, 25.24.
後処理
- filtrationFiltration of the resultant precipitate and recrystallization from ethyl acetate
出典と根拠
- ORDレコード
- ord-899e5b834294457781ff24bde8d37466
- 出典データセット
- uspto-grants-2006_04
- 特許番号
- US07026324B2
反応ノート
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