Hydrochloric Acid → 4-Methyloxan-4-amine hydrochloride
反応式
[N:1]([C:4]1([CH3:10])[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)=C=O.[ClH:11]>C1COCC1>[ClH:11].[CH3:10][C:4]1([NH2:1])[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1参加物
4
実験手順
A solution of 4-isocyanato-4-methyltetrahydro-2H-pyran (D10) (520 mg, 3.68 mmol) in THF (30 mL) was treated with 5 M hydrochloric acid (4.05 mL, 20.3 mmol) and stirred at room temperature overnight. The mixture was then concentrated under vacuum to yield the title compound (D11) (820 mg, 3.52 mmol, 95% yield) as a pale green solid.
後処理
- concentrationThe mixture was then concentrated under vacuum
出典と根拠
- ORDレコード
- ord-08f5c8cf2c31484495c0f5992e00a869
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08344000B2
反応ノート
読み込み中…