Methanol → Benzoic acid, 2,5-diiodo-, methyl ester
反応式
[I:1][C:2]1[CH:10]=[CH:9][C:8]([I:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].O=S(Cl)Cl.[CH3:16]O>>[I:1][C:2]1[CH:10]=[CH:9][C:8]([I:11])=[CH:7][C:3]=1[C:4]([O:6][CH3:16])=[O:5]参加物
4
実験手順
To a solution of 2,5-diiodobenzoic acid (1.00 g, 2.67 mmol) in anhydrous MeOH (15 mL) cooled in an ice-bath, SOCl2 (0.50 mL, 6.85 mmol) was cautiously added (exothermal reaction). After the addition, the solution was heated at reflux overnight. It was then concentrated in vacuo to give methyl 2,5-diiodobenzoate (1.04 g).
後処理
- custom(exothermal reaction)
- additionAfter the addition
- temperaturethe solution was heated
- temperatureat reflux overnight
- concentrationIt was then concentrated in vacuo
出典と根拠
- ORDレコード
- ord-84f4aa5f865d40ccb7c410f66a291a3f
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08349873B2
反応ノート
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