Triethylamine → HCID 54192011、化合物

HRID 1803060ノート

反応式

HRID 1803060 の反応式
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[CH2:9](N(CC)CC)[CH3:10]>C1COCC1>[CH:2]1[N:1]=[CH:10][CH2:9][N:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=12

参加物

4

反応物 2

HCID 8471TriethylamineHCID 195092-Pyridinemethanamine

生成物 1

HCID 54192011HCID 54192011、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

2-aminomethyl pyridine (10 mmol) was dissolved together with triethylamine (20 mmol) in THF (50 ml) and a solution of the corresponding bis-imidoylchloride (10 mmol) was added dropwise. Then the solution was refluxed for ca. 4 h and after cooling-down the solvent was removed under reduced pressure. The residue was washed with little cold methanol and subsequently, the residue was recrystallized from acetonitrile or THF.

後処理

  1. temperatureThen the solution was refluxed for ca. 4 h
  2. temperatureafter cooling-down the solvent
  3. customwas removed under reduced pressure
  4. washThe residue was washed with little cold methanol
  5. customsubsequently, the residue was recrystallized from acetonitrile or THF

出典と根拠

ORDレコード
ord-78cd227edabb4a47b9ff21c79ea7bae2
出典データセット
uspto-grants-2013_01
特許番号
US08350038B2

反応ノート

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