N'-(propan-2-ylidene)(tert-butoxy)carbohydrazide → N'-(propan-2-yl)(tert-butoxy)carbohydrazide

HRID 1816291ノート

反応式

HRID 1816291 の反応式
[CH3:1][C:2](=[N:4][NH:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])[CH3:3]>[Pd].C(O)(=O)C>[CH:2]([NH:4][NH:5][C:6]([O:8][C:9]([CH3:11])([CH3:10])[CH3:12])=[O:7])([CH3:3])[CH3:1]

参加物

4

反応物 1

HCID 11435207N'-(propan-2-ylidene)(tert-butoxy)carbohydrazide

生成物 1

HCID 11217534N'-(propan-2-yl)(tert-butoxy)carbohydrazide

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

1-Methylethylidene-2-tert-butoxycarbonylhydrazine, glacial acetic acid (150 mL) and 10% palladium on carbon (2.0 g) were placed in a 500 mL Parr flask. The bottle was placed on a Parr apparatus, and after evacuating and flushing the bottle with nitrogen three times, the flask was charged with hydrogen to 40 psi. After hydrogen uptake ceased, the flask was evacuated and flushed with nitrogen. Filtration through celite, eluting with ethyl acetate, and concentration afforded the crude 1-(isopropyl)-2-tert-butoxycarbonylhydrazine as an acetic acid salt.

後処理

  1. customafter evacuating
  2. customflushing the bottle with nitrogen three times
  3. additionthe flask was charged with hydrogen to 40 psi
  4. customthe flask was evacuated
  5. customflushed with nitrogen
  6. filtrationFiltration through celite
  7. washeluting with ethyl acetate, and concentration

出典と根拠

ORDレコード
ord-0849324a6ec6451f89c9d51f6e61325f
出典データセット
uspto-grants-2005_04
特許番号
US06884801B1

反応ノート

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